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Imagine a world where natural, personalized “spare parts” could be used to replace damaged tissues or organs, restoring health and vitality to patients with severe diseases. These custom-made biological solutions would not only fit perfectly, but also integrate naturally with the body, reducing the risk of rejection and complications — just like replacing a part in a machine, but with the elegance and precision of nature itself.

47
remaining days
53 investors
Investment achieved
255.750€
Target
700.000€
Invested
36.5%
36.5% INVESTED
Maturity

Premarket/clinical phase

Premoney valuation

29.708.960

Estimated exit

2027

Sector

Personalized medicine

Equity offered

2.3%

Minimum investment

1.000

SE based flag
Equity L
Tax deduction
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Overview: VERIGRAFT

Valuation 29.708.960
Estimated return x13
% Offered 2.3%
Estimated exit 2027

VERIGRAFT’s personalized tissue-engineered grafts do not necessitate any suppression of the patient’s immune system.

Our biological tissue grafts can surpass synthetic grafts with regards to durability and resistance to infection. We provide real tissues, fully natural!

VERIGRAFT’s first product is already in clinical development and the trials are delivering positive safety data as well as exciting therapeutic observations.

Preclinical development of the second advanced therapy product (personalized artery graft) is completed and we are on the way to enter clinical development.

VERIGRAFT’s platform technology produces real products today but also offers enormous opportunities for future therapies.

VERIGRAFT is pioneering personalized tissue therapies that act like custom-made “spare parts” for the human body, revolutionizing treatment for vascular disease.

By transforming donated tissues to match each patient’s biology, VERIGRAFT’s fully natural, tissue-engineered grafts eliminate the need for immunosuppression and reduce risks of rejection and infection — offering life-changing solutions to patients with severe and debilitating conditions for the first time.

VERIGRAFT’s first personalized tissue therapy for the treatment of severe chronic venous insufficiency is in clinical trials. Phase I/II trials demonstrate the safety and efficacy.

The first-of-a-kind clinical trials are performed at multiple university hospitals in Spain. P-TEV grafts with functional venous valves can restore normal blood flow in the legs of patients with chronic venous insufficiency. In this way the underlying cause of the disease is treated and symptoms such as painful swelling and long term ulcers are improved.

With promising clinical trial results and a clear regulatory strategy, the company is on track for market approval in Europe and the USA by 2027, while planning a strategic exit in 2-3 years.

VERIGRAFT’s development pipeline comprises regenerative therapies for several major disease indications.

The company’s innovations are protected by 82 strong patents throughout the world.

VERIGRAFT’s solutions have a vast market potential across multiple important medical fields:

  1. Chronic Venous Insufficiency (CVI): Millions suffer from CVI, with few effective treatments. The market size was valued ~USD 2 billion in 2023 with significant growth over the next decade. VERIGRAFT’s P-TEV™ grafts aim to provide a curative solution, enhancing quality of life and reducing healthcare costs.
  2. Arterial Grafts: Valued at $3 billion in 2022 and projected to reach $4.1 billion by 2026, the arterial graft market sees over 200,000 coronary artery bypass grafting procedures annually in the U.S. VERIGRAFT’s biological grafts offer fewer complications and lower long-term costs.
  3. Dialysis Access: VERIGRAFT’s biological grafts could significantly reduce complications for dialysis patients, improving outcomes over current arteriovenous grafts.
  4. Peripheral Nerve Grafts: The $1.4 billion market for peripheral nerve repair is growing at 7.65% CAGR through 2030. VERIGRAFT’s P-TEN™ grafts address the unmet need for repairing large nerve defects.
  5. Heart Valve Replacement: The heart valve market, valued at $6.9 billion in 2021, is set to reach $19.7 billion by 2031. VERIGRAFT’s personalized heart valves offer a lifelong solution, particularly for younger patients.

With cutting-edge facilities in Gothenburg, Sweden, and a global team of collaborators and advisors, VERIGRAFT is set to reshape the future of regenerative medicine.

VERIGRAFT’s strategic positioning, breakthrough technology, and strong stakeholder support make it a key player in tissue therapies and regenerative medicine. VERIGRAFT is ready to meet critical unmet needs and capture a major share of the global tissue therapy market.

Imagine the transformative impact when surgeons can transplant fully natural, personalized replacement tissues to treat seriously ill patients.

Why is Capital Cell investing in this company?

Chronic Venous Insufficiency (CVI) is a widespread condition with limited effective treatments. Verigraft's innovative decellularization technology allows donated tissue to match the recipient's tissue, eliminating rejection and the need for immunosuppression. Their Personalized Tissue-Engineered Veins (P-TEV) are in Phase I/II clinical trials, showing promising results.

Verigraft's technology is backed by numerous peer-reviewed studies and has potential applications in personalized arteries, nerves, and heart valves. The CVI market is a billion-dollar opportunity with significant unmet needs. Verigraft's strong IP portfolio, with 82 patents protecting them until 2039, and a strategic business plan for global commercialization make them a compelling investment. Market entry is anticipated by 2027, with a high likelihood of success despite some competition.

Minimum investment: 1.000
Type of exit expected: Trade sale
Drag-along rights
Tag-along rights
The SPV will have this right
The SPV will have this right
Tax deductions
VERIGRAFT is based in Swededen. No special tax incentives possible.
Main risks

Although the project shows promising early results, it is still in its middle stages, requiring extensive and costly clinical trials. There is a risk that these trials may not demonstrate the expected efficacy, potentially hindering certification from regulatory bodies such as the FDA.

Additionally, market adoption can be slow as healthcare providers may be reluctant to switch from established treatments, and competing solutions might reach the market sooner or prove more effective.